Advertisements
Homepage_banner_feb2020
Promotional header from the U-Dream website

Introduction

    You might already know about the legal gray-area drugs sold in gas stations and on the internet, usually labeled “not for human consumption” and chemically similar to existing hard drugs. Examples of these include things like “Spice“, “Bath salts” and “Flakka“. These substances have long been a talking point in America, and they swing in and out of the public eye with each new controversial substance.

    Aside from this, did you know that there have been plenty of companies selling unscheduled “research chemicals” as an unmentioned ingredient in over-the-counter supplements? These chemicals that find their way into legal blends are often drugs that address the issues the supplement is purported to assist with.

Recall of “U-Dream” Herbal Sleep Aid

(source)

    In December of 2019, news broke in Canada that a popular natural sleep product was investigated by Health Canada after more than one user suffered serious cardiac events on it, including one man who died and was revived. An investigation found that the supposedly “all natural” product contained the sedative herbs it advertised, as well as a chemical that Health Canada named “Zopiclone Impurity 22“. This chemical is structurally similar to existing sleeping drug Zopiclone, hence the name. On the day before Christmas Eve, all derivatives of “Udream Herbal” were recalled effective immediately.

Lunesta and Imovane / Zopiclone and Eszopiclone

    Zopiclone is a popular anti-insomnia drug available outside of the U.S. as the prescription drug “Imovane”. In America, people are prescribed a well-known version of Zopiclone called Eszopiclone, which is branded “Lunesta” (and sometimes available generically). Zopiclone is classified as a “nonbenzodiazipene” drug, which are structurally distinct from benzodiazepines like Xanax and Valium.

Sleep Aid Must Carry Warning About Drowsiness, FDA Says
Bottle of Lunesta / Eszopiclone tablets (source)
Imovane for sale online – Intruehealth.com
Box of Imovane / Zopiclone tablets (source)

    This class of drugs is distinguished as such due to it’s effects, which are ironically very similar to those of benzodiazepines. These drugs work because they agonize certain GABA receptors in our brain, the receptors specifically responsible for regulating our anxiety and fear levels. Zopiclone is not as recreational as “benzos” but the potential is still there. It’s mechanism of action also causes it to be a very physically addictive drug.

What’s the Catch with “Zopiclone Impurity 22”?

    “Zopiclone Impurity 22” is the official identifier for a virtually unknown chemical that has never been studied or marketed as a drug. It’s molecular formula is C17H17BrN6O3, while the formula for Zopiclone is C17H17ClN6O3. Eszopiclone and Zopiclone share the same formula but differ structurally by a single bonding point. The main difference seen in “Zopiclone Impurity 22” is that a single Chlorine atom is replaced with Bromine.

    Although a small change to a chemical can sometimes drastically change it’s properties, it seems as if the pharmacological action of this chemical is almost the same as it’s parent. 

(source)
Advertisements

The Result

    While it was available, the U-Dream brand was selling one of the most popular and demanded sleep products you can buy in Canada. Reviews of it tout it constantly as being the best thing you can buy for sleep. Some anecdotes describe absolutely desperate users had tried countless products (including prescription drugs) and had no success until they found U-Dream.

In the first review seen on this list from Well.ca, one user foreshadows the news about the U-Dream Herbal product but believes it to be caused by the plethora of “adaptogen” agents.

    The U-Dream website now contains an official statement on the news. They address the product being made illegal overnight Canada-wide, and deny the intentional addition of “Zopiclone Impurity 22”. They state that they are eager to get their product back on the market and are cooperating with Health Canada to the fullest. One has to wonder if the new version of the product will be even a tenth as effective without the magic Zopiclone-like ingredient.

Official ingredient list for “U-Dream Herbal” sleep aid, as found on their website.
The website also contains a heavily cautioning disclaimer about the way to use the product. They warn strongly against mixing it with other depressants and using it for longer than a very brief period. These types of cautions are somewhat unusual for the benign products “U-Dream Herbal” is made up of, and are more indicative of the intentional presence of “Zopiclone Impurity 22”.

Read More about “Zopiclone Impurity 22”:

About Zopiclone Impurity 22 – Zodiac Life Sciences

About Zopiclone Impurity 22 – CYMIT QUÍMICA

“Zopiclone Impurity 22” – discussion on /r/researchchemicals

Similar Articles

Powdered Dopamine and Serotonin are Real Things, and You Can Buy Them

Powdered dopamine and serotonin is something real in medicine, just not for what you would think. These hydrochloride salts do have legitimate uses, however.

Updated: Nipsey Hussle Ecstasy Pills Now on the Streets

KanyeToThe user shows off Nipsey Hussle ecstasy pill, just in time for the Nipsey tribute during tonight’s BET Awards. Read more about “Nipsey Blues”…

Advertisements

More from UrbanTrueCrime.com

Is this gang member’s Halloween costume a rival’s dead body? 600 vs 051 Young Money (Chicago)

A member of 051 Young Money in Chicago disses his deceased rival by mocking the circumstances of his murder.

Details That Most Missed in the YSL Indictment

Yak Gotti and Lil Duke are facing murder conspiracy charges for picking up guns and sliding, but not finding anyone. Someone associated with YSL almost got “backdoored” in jail. Read about the big details in the 2022 YSL indictment on UrbanTrueCrime.com.

Arkansas Rapper Cee Kay Arrested for Alleged Shooting Involving Security Guard Last Year

The Hikari-Ultra rapper Cee Kay was once subject to a viral SayCheese interview, an NBA YoungBoy collaboration and several hit singles, Jail stints in the Arkansas system and shooting incidents would prove to almost fully stagnate his career by 2022.

OBlock BossTop Regrets Incriminating Interview After FBG Duck’s Murder

A since deleted interview from an unknown Chi-town cameraman captured Oblock BossTop saying some certainly regrettable things on the topic of FBG Duck’s then-recent murder.

A Look at 9 Rare & Interesting Pharmaceutical Drugs

WeaponsG.com has compiled a collection of images showing off nine incredibly rare pharmaceutical drugs, with most of them being time pieces at this point. This article is possible because of the incredibly interesting /r/ObscureDrugs community on Reddit.

Who is Squiidape? One of The Most Followed Chicago Drill Outlets is a French Collective

For years now, the curiously named “Squiidape” blog has been a dominating news source for the french drill fans out there, represented by a handful of young France-based men who are obviously some of the biggest appreciators of the music.

WeaponsG.com Releases Tool For Site Owners to Tackle Social Media With

WeaponsG.com’s is pleased to share with the world “Thumbnail Generator”, a lightweight Windows 10 application used to create social media posts for news sites or blogs.

Random: Abandoned Mausoleum in Polish Park Once Housed a Monster

In a publicly accessible park in Poland, locals could venture to a somewhat remote forest area and find a small mausoleum (in disrepair) with more than a century of history. Upon entrance between 2016 and 2019, one was confronted by an abandoned Polish monster statue.

Failed Kidnapping Aftermath in Kentucky Gets Little Media Coverage

An alleged failed kidnapping in Lexington, Kentucky is making the rounds on Reddit recently after a video circulated showing a frantic young girl being assisted with removing tape from her hands and head in the middle of a street.

VIRAL: Man Drops Pound of Weed All Over Car

A video is going viral since yesterday (924K views currently) showing the aftermath of a man dropping a pound of weed all over his car.

Florida Politician KW Miller Connects EDM to Opioid Crisis

A Florida congressional candidate named KW Miller tried to link dance music with America’s opioid crisis this week, to much dismay.

Federal Judge Esther Salas Targeted by Hit, Son Killed and Husband Shot

A lone gunman dressed as a FedEx driver targeted the home of a New Jersey federal judge named Esther Salas yesterday, shooting and killing her son Daniel Anderl at the doorstop. Her husband Mark Anderl was also shot and critically wounded.

Gang Member Unknowingly Exposes Self as Federal Informant During Court Livestream

An alleged member of the Latino Chicago gang “Two Six” recently appeared for a digital court date over Zoom and exposed himself as a federal informant on the livestream. The judge among others quickly caught the man and gave him a stern notice that his court date was being broadcast on YouTube.

Lil Moe of Chicago Was Making Noise Before Music

Lil Moe is only 15 years old, and after uploading his first music video midway through June of this year (“6 Blocka”) he has already amassed hundreds of thousands of views. Fans are now hopeful for a Lil Moe rap career, but Lil Moe had his fame already from the “streets” side of the Chicago drill landscape.

Mieyoshi “Lit Yoshi” Edwards Arrested for Shootings That Injured Kids

Baton Rouge rapper and Fredo Bang affiliate Mieyoshi “Lit Yoshi” Edwards was arrested in his hometown recently, accused of two shootings that injured five people (including two children).